Controlled therapeutic trial to determine the optimum dose of antacids in duodenal ulcer.

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Controlled therapeutic trial to determine the optimum dose of antacids in duodenal ulcer.

Antacids are widely used in the management of duodenal ulcer but the optimum dose of antacid required for ulcer healing has not been determined. We therefore studied 107 patients with endoscopically diagnosed duodenal ulcer who were allotted at random to one of the following treatment groups; placebo (group P) and antacid (groups A, B and C). A liquid antacid (Aludrox MH, Wyeth) with neutralisi...

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Sixty patients, whose duodenal ulcers had healed endoscopically after six weeks of treatment with cimetidine 1 g/day in divided doses, were treated with maintenance cimetidine 800 mg at bedtime for six months. Eighteen relapsed endoscopically (30%). Of the 42 still in remission, 36 then completed a six month double-blind comparison of bedtime cimetidine 400 mg and placebo. Twelve of the 19 (63%...

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Randomised controlled trial of short term treatment to eradicate Helicobacter pylori in patients with duodenal ulcer.

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ژورنال

عنوان ژورنال: Gut

سال: 1984

ISSN: 0017-5749

DOI: 10.1136/gut.25.11.1199